The key to a long life? "Test first, supplement second" (2026)

The quest for longevity has become a booming industry, with countless products and treatments promising to turn back the clock on aging. But amidst the hype and the sales pitches, a group of leading scientists gathered at the Longevity Summit in Dublin to offer a different perspective.

In this article, we delve into the insights shared by these experts, who approach the topic with a healthy dose of skepticism and a focus on evidence-based practices.

The Boring Consensus: Lifestyle Matters

When asked about the secrets to longevity, the scientists' advice is surprisingly mundane. Dr. Matt Kaeberlein, an aging researcher and founder of the Dog Aging Institute, emphasizes the importance of lifestyle choices. He advocates for a high-quality diet, regular exercise, good sleep, social connections, and stress management.

"It starts with lifestyle. Eat well, move your body, get enough rest, and nurture your relationships. These are the building blocks of a long and healthy life."

Dr. Eric Verdin, director of the Buck Institute for Research on Aging, echoes this sentiment, adding that simple activities like walking for 15 minutes twice a day can have a massive impact on health, surpassing any supplement.

The Power of Sleep and Social Connections

Sleep, often overlooked, is a key component of longevity, according to Kennedy Schaal, founder of Rejuve Biotech. Dr. Rozalyn Anderson, a professor at the University of Wisconsin-Madison, takes a pragmatic approach, suggesting that weight gain is a reliable indicator of health, and a nudge to make healthier choices.

The importance of social connections also emerged as a theme. Martin O'Dea, founder of the Longevity Summit, highlighted the harmful effects of isolation on older individuals, emphasizing the need for social engagement.

Test Before You Supplement

One of the most intriguing insights from the scientists is their focus on testing before supplementation. Dr. Kaeberlein suggests measuring blood markers like fasting insulin and ApoB, which indicate cardiovascular health, before considering supplements.

"If you can measure it in your blood and it's not in the optimal range, then supplementing to reach that range makes sense."

O'Dea reinforces this idea, emphasizing the need for personalized testing, as there is no one-size-fits-all approach to health.

Scams and Snake Oil

The scientists were particularly vocal about the scams and unproven treatments circulating in the longevity market. Dr. Kaeberlein dismisses IV drips, peptides, and NAD infusions as lacking compelling evidence of individual benefits. Dr. Verdin is even more blunt, calling IV infusions "medical scams in a white coat."

The supplement industry also comes under fire, with Dr. Kaeberlein criticizing the incentives for companies to mislead consumers. He warns against believing influencers who promote these products without scientific backing.

What's Coming: Human Clinical Trials

Despite the skepticism, the scientists are optimistic about the future of longevity research. Dr. Kaeberlein's work with rapamycin, a drug that has shown promise in slowing aging in the lab, is a prime example. The focus is now on human clinical trials, which will provide real-world evidence of the effectiveness of these interventions.

The Secret to Longevity: It's Simple and Affordable

In the end, the secret to a long life is not a mysterious pill or injection. It's a combination of healthy habits, social connections, and personalized testing. As Dr. Anderson puts it, "mortality is still at 100%, but how we age is not inevitable."

"The trajectory of aging can be changed. It's within our control, and it doesn't have to cost a fortune."

So, the next time you're tempted by a longevity product or treatment, remember the wisdom of these scientists: test first, supplement second, and prioritize the simple, evidence-based practices that truly promote health and longevity.

The key to a long life? "Test first, supplement second" (2026)
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